Post-chemotherapy C-reactive protein/albumin ratio predicts prognosis in stage II-III colorectal cancer

doi:10.4240/wjgs.v18.i2.112924

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World Journal of Gastrointestinal Surgery

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1948-9366

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©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Feb 27, 2026; 18(2): 112924
Published online Feb 27, 2026. doi: 10.4240/wjgs.v18.i2.112924

Table 2 The relationship between the C-reactive protein/albumin ratio, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, systemic immune-inflammation index and clinicopathological characteristics in II/III patients with colorectal cancer

		Age	Sex		Site		CEA (ng/mL)		TNM
		Age	Female	Male	Colon	Rectum	< 5	≥ 5	II	III
CAR	Low	61.74	95	135	165	65	160	70	95	135
Pre-operation	Low	61.74	95	135	165	65	160	70	95	135
	High	61.93	105	110	140	75	95	120	85	130
	P value	0.86	0.5266		0.6483		0.0192		0.9999
NLR	Low	62.76	75	70	80	65	95	50	55	90
Pre-operation	Low	62.76	75	70	80	65	95	50	55	90
	High	61.38	125	175	225	75	160	140	125	175
	P value	0.23	0.4957		0.0874		0.3616		0.2918
PLR	Low	63.38	140	120	155	105	165	95	110	100
Pre-operation	Low	63.38	140	120	155	105	165	95	110	100
	High	59.65	60	125	150	35	90	95	70	115
	P value	0.0006	0.0054		0.0385		0.1953		0.8268
SII	Low	61.93	30	40	40	30	50	20	40	30
Pre-operation	Low	61.93	30	40	40	30	50	20	40	30
	High	61.81	170	205	265	110	205	170	140	235
	P value	0.94	0.9999		0.3553		0.3782		0.2359

CEA: Carcinoembryonic antigen; TNM: Tumor-node-metastasis; CAR: C-reactive protein/albumin ratio; NLR: Neutrophil-to-lymphocyte ratio; PLR: Platelet-to-lymphocyte ratio; SII: Systemic immune-inflammation index.

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Citation: Kong FF, Geng X, Liu RM, Zhang WT, Quan B, Zhong Y, Zhu YL. Post-chemotherapy C-reactive protein/albumin ratio predicts prognosis in stage II-III colorectal cancer. World J Gastrointest Surg 2026; 18(2): 112924
URL: https://www.wjgnet.com/1948-9366/full/v18/i2/112924.htm
DOI: https://dx.doi.org/10.4240/wjgs.v18.i2.112924

Kong FF, Geng X, Liu RM, Zhang WT, Quan B, Zhong Y, Zhu YL. Post-chemotherapy C-reactive protein/albumin ratio predicts prognosis in stage II-III colorectal cancer. World J Gastrointest Surg 2026; 18(2): 112924 [PMID: 41809326 DOI: 10.4240/wjgs.v18.i2.112924]

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