Efficacy of endoscopic submucosal dissection in the treatment of early gastrointestinal lesions

doi:10.4240/wjgs.v18.i2.112776

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Feb 27, 2026; 18(2): 112776
Published online Feb 27, 2026. doi: 10.4240/wjgs.v18.i2.112776

Table 8 Comparison of gastrointestinal hormones and intestinal mucosal barrier indicators between two groups before and after surgery (7 days after surgery), mean ± SD

Parameters	Gastrectomy (n = 98)	ESD (n = 108)	t	P value
VIP (ng/L)	103.55 ± 10.36	103.53 ± 12.96	0.014	0.989
GAS (ng/L)	16.23 ± 2.25	16.11 ± 2.63	0.325	0.746
MTL (ng/L)	258.93 ± 28.77	257.00 ± 25.93	0.616	0.539
DAO (U/mL)	1.69 ± 0.22	1.68 ± 0.12	0.317	0.752
ET (EU/mL)	0.34 ± 0.04	0.33 ± 0.04	0.866	0.388
NO (μmol/L)	75.69 ± 8.35	76.89 ± 8.33	1.031	0.304
D-Lac (μg/mL)	11.63 ± 1.36	11.18 ± 1.31	2.445	0.015

VIP: Vasoactive intestinal peptide; GAS: Gastrin; MTL: Motilin; DAO: Diamine oxidase; ET: Endotoxin; NO: Nitric oxide; D-Lac: D-lactic acid; ESD: Endoscopic submucosal dissection.

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Citation: Ling Y, Wang J, Xi CH, Liu J. Efficacy of endoscopic submucosal dissection in the treatment of early gastrointestinal lesions. World J Gastrointest Surg 2026; 18(2): 112776
URL: https://www.wjgnet.com/1948-9366/full/v18/i2/112776.htm
DOI: https://dx.doi.org/10.4240/wjgs.v18.i2.112776

Ling Y, Wang J, Xi CH, Liu J. Efficacy of endoscopic submucosal dissection in the treatment of early gastrointestinal lesions. World J Gastrointest Surg 2026; 18(2): 112776 [PMID: 41809361 DOI: 10.4240/wjgs.v18.i2.112776]

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