Efficacy of endoscopic submucosal dissection in the treatment of early gastrointestinal lesions

doi:10.4240/wjgs.v18.i2.112776

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Feb 27, 2026; 18(2): 112776
Published online Feb 27, 2026. doi: 10.4240/wjgs.v18.i2.112776

Table 7 Comparison of gastrointestinal hormones and intestinal mucosal barrier indicators between two groups before and after surgery (3 days after surgery), mean ± SD

Parameters	Gastrectomy (n = 98)	ESD (n = 108)	t	P value
VIP (ng/L)	95.66 ± 9.11	96.33 ± 13.25	0.423	0.673
GAS (ng/L)	13.66 ± 1.99	13.88 ± 2.01	0.773	0.44
MTL (ng/L)	235.96 ± 26.17	236.33 ± 28.71	0.098	0.922
DAO (U/mL)	2.05 ± 0.33	1.92 ± 0.26	3.249	0.001
ET (EU/mL)	0.33 ± 0.05	0.34 ± 0.04	2.187	0.030
NO (μmol/L)	79.26 ± 9.33	79.55 ± 8.21	0.235	0.814
D-Lac (μg/mL)	12.56 ± 1.77	12.03 ± 1.36	2.37	0.019

VIP: Vasoactive intestinal peptide; GAS: Gastrin; MTL: Motilin; DAO: Diamine oxidase; ET: Endotoxin; NO: Nitric oxide; D-Lac: D-lactic acid; ESD: Endoscopic submucosal dissection.

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Citation: Ling Y, Wang J, Xi CH, Liu J. Efficacy of endoscopic submucosal dissection in the treatment of early gastrointestinal lesions. World J Gastrointest Surg 2026; 18(2): 112776
URL: https://www.wjgnet.com/1948-9366/full/v18/i2/112776.htm
DOI: https://dx.doi.org/10.4240/wjgs.v18.i2.112776

Ling Y, Wang J, Xi CH, Liu J. Efficacy of endoscopic submucosal dissection in the treatment of early gastrointestinal lesions. World J Gastrointest Surg 2026; 18(2): 112776 [PMID: 41809361 DOI: 10.4240/wjgs.v18.i2.112776]

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