Efficacy of endoscopic submucosal dissection in the treatment of early gastrointestinal lesions

doi:10.4240/wjgs.v18.i2.112776

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Feb 27, 2026; 18(2): 112776
Published online Feb 27, 2026. doi: 10.4240/wjgs.v18.i2.112776

Table 6 Comparison of gastrointestinal hormones and intestinal mucosal barrier indicators before and after surgery between two groups (preoperative), mean ± SD

Parameters	Gastrectomy (n = 98)	ESD (n = 108)	t	P value
VIP (ng/L)	139.36 ± 16.13	138.84 ± 15.33	0.235	0.815
GAS (ng/L)	16.78 ± 2.53	16.97 ± 2.58	0.533	0.595
MTL (ng/L)	296.33 ± 32.01	298.35 ± 30.84	0.461	0.645
DAO (U/mL)	1.33 ± 0.19	1.36 ± 0.21	1.055	0.293
ET (EU/mL)	0.21 ± 0.03	0.22 ± 0.05	1.053	0.294
NO (μmol/L)	62.33 ± 7.68	63.02 ± 7.39	0.654	0.514
D-Lac (μg/mL)	9.11 ± 1.32	8.65 ± 1.17	2.623	0.009

VIP: Vasoactive intestinal peptide; GAS: Gastrin; MTL: Motilin; DAO: Diamine oxidase; ET: Endotoxin; NO: Nitric oxide; D-Lac: D-lactic acid; ESD: Endoscopic submucosal dissection.

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Citation: Ling Y, Wang J, Xi CH, Liu J. Efficacy of endoscopic submucosal dissection in the treatment of early gastrointestinal lesions. World J Gastrointest Surg 2026; 18(2): 112776
URL: https://www.wjgnet.com/1948-9366/full/v18/i2/112776.htm
DOI: https://dx.doi.org/10.4240/wjgs.v18.i2.112776

Ling Y, Wang J, Xi CH, Liu J. Efficacy of endoscopic submucosal dissection in the treatment of early gastrointestinal lesions. World J Gastrointest Surg 2026; 18(2): 112776 [PMID: 41809361 DOI: 10.4240/wjgs.v18.i2.112776]

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