Serum inflammatory biomarkers can predict clinical outcomes in patients with sepsis-associated gastrointestinal dysfunction

doi:10.4240/wjgs.v18.i2.112169

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Feb 27, 2026; 18(2): 112169
Published online Feb 27, 2026. doi: 10.4240/wjgs.v18.i2.112169

Table 4 Multivariate analysis of clinical outcome predictors in septic patients with gastrointestinal dysfunction

Indicators	β	SE	Wald	P value	OR	95%CI
PCT (ng/mL)	0.102	0.078	1.699	0.192	1.107	0.950-1.291
CRP (mg/L)	0.006	0.005	5.742	0.017	1.006	1.001-1.010
IL-6 (ng/L)	0.016	0.009	3.357	0.067	1.016	0.999-1.034
IL-10 (pg/mL)	0.003	0.002	2.366	0.124	1.003	0.999-1.007
TNF-α (μg/L)	0.006	0.002	9.603	0.002	1.006	1.002-1.010
APACHE II (points)	0.027	0.022	1.516	0.218	1.028	0.984-1.074
SOFA (points)	0.074	0.032	5.214	0.022	1.077	1.011-1.148

PCT: Procalcitonin; CRP: C-reactive protein; IL: Interleukin; TNF-α: Tumor necrosis factor-alpha; APACHE II: Acute Physiology and Chronic Health Evaluation II; SOFA: Sequential Organ Failure Assessment; OR: Odds ratio; CI: Confidence interval.

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Citation: Liu YH, Chen QY, Dai FY, Chen XY. Serum inflammatory biomarkers can predict clinical outcomes in patients with sepsis-associated gastrointestinal dysfunction. World J Gastrointest Surg 2026; 18(2): 112169
URL: https://www.wjgnet.com/1948-9366/full/v18/i2/112169.htm
DOI: https://dx.doi.org/10.4240/wjgs.v18.i2.112169

Liu YH, Chen QY, Dai FY, Chen XY. Serum inflammatory biomarkers can predict clinical outcomes in patients with sepsis-associated gastrointestinal dysfunction. World J Gastrointest Surg 2026; 18(2): 112169 [PMID: 41809344 DOI: 10.4240/wjgs.v18.i2.112169]

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