Silencing of thrombospondin-1 prevents abdominal adhesion formation by reducing inflammation and oxidative stress

Figure 1 Thrombospondin-1 expression is increased in adhesion tissues after peritoneal injury in mice (four groups, n = 5 mice/group). A: Representative images showing the gross postoperative abdominal adhesion conditions 1 day, 3 days, 5 days, and 7 days after peritoneal injury. The arrows indicate adhesive tissue; B: Typical hematoxylin-eosin staining images of adhesion tissues 1 day, 3 days, 5 days, and 7 days after peritoneal injury; C: Typical immunohistochemistry (IHC) staining images of thrombospondin-1 on 1 day, 3 days, 5 days, and 7 days after surgery; D: Nair’s score in different groups; E: Inflammation score in different groups; F: IHC staining score of thrombospondin-1.