Intraoperative frozen section diagnosis of primary alpha-fetoprotein–positive hepatoid adenocarcinoma of the gallbladder: A case report

Figure 3 Routine pathological sections of hepatoid adenocarcinoma. A: Solid and cord-like hepatoid differentiation pattern of tumor cells; B: Ring-like cancer cell morphology; C: Moderately differentiated glandular and papillary structures; D: Perineural invasion (tumor cells encircling a nerve bundle) and microvascular invasion (tumor embolus within a small blood vessel). A-D: Hematoxylin and eosin staining, × 400.