Preventive strategies for post-endoscopic retrograde cholangiopancreatography pancreatitis: A systematic review and meta-analysis

doi:10.4240/wjgs.124443

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Meta-Analysis

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Nov 27, 2026; 18(11): 124443
Published online Nov 27, 2026. doi: 10.4240/wjgs.124443

Table 2 Major quantitative findings

Analysis	Trials	Intervention events/total	Control events/total	Pooled RR (95%CI)	Heterogeneity
Overall PEP prevention	14	93/2374	249/2414	0.38 (0.30-0.48)	I² = 0%; P = 0.77
NSAID/pharmacologic prophylaxis	10	77/2095	192/2135	0.41 (0.32-0.52)	I² = 0%; P = 0.85
Pancreatic duct stent	3	16/243	55/243	0.31 (0.20-0.48)	I² = 0%; P = 0.98
Traditional Chinese medicine/other	1	0/36	2/36	0.20 (0.01-4.03)	Not applicable

RR: Risk ratio; CI: Confidence interval; PEP: Post-endoscopic retrograde cholangiopancreatography pancreatitis; NSAIDs: Non-steroidal anti-inflammatory drugs.

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Citation: Wang XY, Liu YY, Zhang YF, Zhou XQ, Sun MC, Zheng Q. Preventive strategies for post-endoscopic retrograde cholangiopancreatography pancreatitis: A systematic review and meta-analysis. World J Gastrointest Surg 2026; 18(11): 124443
URL: https://www.wjgnet.com/1948-9366/full/v18/i11/124443.htm
DOI: https://dx.doi.org/10.4240/wjgs.124443

Wang XY, Liu YY, Zhang YF, Zhou XQ, Sun MC, Zheng Q. Preventive strategies for post-endoscopic retrograde cholangiopancreatography pancreatitis: A systematic review and meta-analysis. World J Gastrointest Surg 2026; 18(11): 124443 [DOI: 10.4240/wjgs.124443]

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