Impact of perioperative Helicobacter pylori eradication therapy on long-term survival after distal gastrectomy for gastric cancer

doi:10.4240/wjgs.124292

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World Journal of Gastrointestinal Surgery

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1948-9366

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Retrospective Cohort Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Nov 27, 2026; 18(11): 124292
Published online Nov 27, 2026. doi: 10.4240/wjgs.124292

Table 6 Comparison of remnant gastric lesions at 1 year postoperatively, n (%)/mean ± SD

Parameters	Non-eradication group (n = 143)	Eradication group (n = 128)	t/χ²	P value
Atrophy score (0-3)	1.86 ± 0.60	1.44 ± 0.48	7.077	< 0.001
Intestinal metaplasia score (0-3)	1.67 ± 0.56	1.26 ± 0.42	8.045	< 0.001
Bile reflux grade			0.409	0.938
Absent	98 (68.53)	92 (71.88)
Mild	30 (20.98)	24 (18.75)
Moderate	12 (8.39)	10 (7.81)
Severe	3 (2.10)	2 (1.56)
Remnant gastritis severity			7.978	0.046
Absent	28 (19.58)	38 (29.69)
Mild	64 (44.76)	62 (48.44)
Moderate	36 (25.17)	22 (17.19)
Severe	15 (10.49)	6 (4.69)
Anastomotic ulcer	15 (10.49)	4 (3.13)	5.619	0.018

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Citation: Shi RC, Jin D, Su D, Yang XT, Wang X, Hao JF, Yang ZW. Impact of perioperative Helicobacter pylori eradication therapy on long-term survival after distal gastrectomy for gastric cancer. World J Gastrointest Surg 2026; 18(11): 124292
URL: https://www.wjgnet.com/1948-9366/full/v18/i11/124292.htm
DOI: https://dx.doi.org/10.4240/wjgs.124292

Shi RC, Jin D, Su D, Yang XT, Wang X, Hao JF, Yang ZW. Impact of perioperative Helicobacter pylori eradication therapy on long-term survival after distal gastrectomy for gastric cancer. World J Gastrointest Surg 2026; 18(11): 124292 [DOI: 10.4240/wjgs.124292]

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