Construction and validation of a prognostic prediction model based on albumin-bilirubin grade after resection of hepatocellular carcinoma

Table 3 Univariate regression analysis of recurrence-free survival in patients after hepatocellular carcinoma resection

Variables	β	SE	Wald	P value	HR (95%CI)
Sex	0.452	0.197	5.261	0.022	1.571 (1.068-2.312)
Age	0.023	0.008	7.802	0.005	1.023 (1.007-1.039)
Body mass index	-0.010	0.028	0.118	0.732	0.990 (0.937-1.047)
Smoking history	-0.118	0.160	0.544	0.461	0.888 (0.649-1.216)
Alcohol use	-0.044	0.156	0.179	0.778	0.957 (0.705-1.299)
History of diabetes	0.110	0.208	0.279	0.597	1.116 (0.742-1.679)
Family history	0.180	0.215	0.701	0.402	1.197 (0.785-1.826)
History of liver cirrhosis	0.398	0.148	7.247	0.007	1.489 (1.114-1.989)
History of hepatitis B	-0.013	0.148	0.008	0.929	0.987 (0.739-1.318)
Tumor size	0.226	0.073	9.536	0.002	1.254 (1.086-1.447)
Tumor number	0.373	0.156	5.714	0.017	1.452 (1.069-1.972)
Portal hypertension	0.182	0.197	0.851	0.356	1.199 (0.815-1.764)
Vascular invasion	0.385	0.164	5.519	0.019	1.469 (1.066-2.026)
Perineural invasion	0.029	0.255	0.013	0.910	1.029 (0.625-1.695)
Degree of differentiation	0.282	0.117	5.795	0.016	1.326 (1.054-1.668)
Child-Pugh class	-0.189	0.174	1.172	0.279	0.828 (0.589-1.165)
AFP	0.004	0.001	17.381	< 0.001	1.004 (1.002-1.006)
DCP	-0.001	0.002	0.379	0.538	0.999 (0.994-1.003)
ALT	-0.002	0.008	0.043	0.835	0.998 (0.984-1.013)
AST	-0.002	0.008	0.071	0.790	0.998 (0.983-1.013)
TBIL	-0.011	0.019	0.357	0.55	0.989 (0.953-1.026)
Albumin	-0.025	0.013	3.965	0.046	0.975 (0.951-1.000)
ALBI grade	0.576	0.157	13.514	< 0.001	1.779 (1.309-2.419)

HR: Hazard ratio; CI: Confidence interval; AFP: Preoperative alpha-fetoprotein; DCP: Des-gamma-carboxy prothrombin; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; TBIL: Total bilirubin; ALBI: Albumin-bilirubin.