Expression and role of the long noncoding RNA Linc00909 in chemoradiotherapy for colorectal cancer

Figure 6 Bioinformatic prediction of microRNAs that interact with Linc00909 and their downstream target genes. A and B: Gene Ontology and Kyoto Encyclopedia of Genes and Genomes enrichment analyses were performed based on the significantly differentially expressed genes identified between the chemosensitive and chemoresistant groups; C: Bioinformatic analysis was used to predict microRNAs that may bind to Linc00909 and their downstream target genes; D and E: The expression levels of miR-625-5p and SOX2 were quantified by real-time quantitative polymerase chain reaction; F-I: SOX2 protein expression was analyzed by western blotting. ^aP < 0.05, ^cP < 0.001. CON: Control; OE: Overexpression; VEC: Vector control.