Expression and role of the long noncoding RNA Linc00909 in chemoradiotherapy for colorectal cancer

Figure 4 Linc00909 modulates the sensitivity of rectal cancer cells to 5-fluorouracil and radiotherapy. A: Sensitivity to 5-fluorouracil was assessed using a Cell Counting Kit-8 assay in all cell lines; B: Sensitivity to radiation was assessed using a Cell Counting Kit-8 assay in all cell lines; C and D: Radiosensitivity across all cell lines was assessed using a Cell Counting Kit-8 assay. Apoptosis in SW620 cells following treatment with 5-fluorouracil and radiotherapy was analyzed by flow cytometry (C). Apoptosis in DLD1 cells following treatment with 5-fluorouracil and radiotherapy was analyzed by flow cytometry (D). ^aP < 0.05, ^bP < 0.01, ^cP < 0.001, ^dP < 0.0001. CON: Control; OE: Overexpression; VEC: Vector control.