Aggressive pediatric solid pseudopapillary neoplasms of the pancreas presented as acute abdomen: A case report and review of literature

Figure 2 Histopathology and immunohistochemical examination of the tumor tissue removed after the surgery. A: Hematoxylin-eosin (HE) staining (× 40), pseudopapillary structures with fibrovascular cores, lined by poorly cohesive tumor cells; B: HE staining (× 40), tumor with hemorrhage, necrosis, and cholesterol clefts; C: HE staining (× 40), tumor cells infiltrating pancreatic parenchyma; D: Immunohistochemistry (IHC) (× 100), tumor cells showing nuclear progesterone receptor positivity; E: IHC (× 200), tumor cells demonstrating nuclear and cytoplasmic β-catenin positivity; F: IHC (× 200), tumor cells with cytoplasmic Vimentin expression. Scale bars: 200 μm in A-C; 100 μm in D; 50 μm in E and F.