Recurrence risk prediction of small-molecule drugs plus chemo in postoperative gastric cancer: Retrospective analysis via molecular markers

doi:10.4240/wjgs.122160

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Oct 27, 2026; 18(10): 122160
Published online Oct 27, 2026. doi: 10.4240/wjgs.122160

Table 5 Values of molecular markers for recurrence prediction

Variable	AUC	95%CI	Sensitivity	Specificity	Cut-off value
PD-L1 positivity	0.698	0.613-0.774	76.3	63.3	-
TMB	0.934	0.878-0.969	78.95	95.92	≥ 12.37
Combined detection	0.983	0.945-0.998	94.97	98.98	-

PD-L1: Programmed death-ligand 1; TMB: Tumor mutation burden.

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Citation: Yang Y, Liu HD, Yang XY, Li X, Cui LJ. Recurrence risk prediction of small-molecule drugs plus chemo in postoperative gastric cancer: Retrospective analysis via molecular markers. World J Gastrointest Surg 2026; 18(10): 122160
URL: https://www.wjgnet.com/1948-9366/full/v18/i10/122160.htm
DOI: https://dx.doi.org/10.4240/wjgs.122160

Yang Y, Liu HD, Yang XY, Li X, Cui LJ. Recurrence risk prediction of small-molecule drugs plus chemo in postoperative gastric cancer: Retrospective analysis via molecular markers. World J Gastrointest Surg 2026; 18(10): 122160 [DOI: 10.4240/wjgs.122160]

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