Recurrence risk prediction of small-molecule drugs plus chemo in postoperative gastric cancer: Retrospective analysis via molecular markers

doi:10.4240/wjgs.122160

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World Journal of Gastrointestinal Surgery

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1948-9366

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Retrospective Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Oct 27, 2026; 18(10): 122160
Published online Oct 27, 2026. doi: 10.4240/wjgs.122160

Table 2 Comparison of molecular biomarker detection results between the two groups, n (%) or mean ± SD

Baseline characteristics	Recurrence group (n = 38)	Non-recurrence group (n = 98)	χ²/t	P value
CEA (ng/mL)	39.65 ± 4.17	38.79 ± 4.52	1.017	0.311
AFP (ng/mL)	23.17 ± 3.92	22.83 ± 4.05	0.443	0.658
PD-L1 positivity			13.322	< 0.001
Positive	29 (76.32)	36 (40.91)
Negative	9 (23.68)	52 (59.09)
CA125 (U/mL)	30.17 ± 2.94	29.56 ± 3.18	1.025	0.307
TMB (mut/Mb)	14.51 ± 2.82	10.13 ± 1.56	16.782	< 0.001

CEA: Carcinoembryonic antigen; AFP: Alpha-fetoprotein; PD-L1: Programmed death-ligand 1; TMB: Tumor mutation burden.

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Citation: Yang Y, Liu HD, Yang XY, Li X, Cui LJ. Recurrence risk prediction of small-molecule drugs plus chemo in postoperative gastric cancer: Retrospective analysis via molecular markers. World J Gastrointest Surg 2026; 18(10): 122160
URL: https://www.wjgnet.com/1948-9366/full/v18/i10/122160.htm
DOI: https://dx.doi.org/10.4240/wjgs.122160

Yang Y, Liu HD, Yang XY, Li X, Cui LJ. Recurrence risk prediction of small-molecule drugs plus chemo in postoperative gastric cancer: Retrospective analysis via molecular markers. World J Gastrointest Surg 2026; 18(10): 122160 [DOI: 10.4240/wjgs.122160]

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