Recurrence risk prediction of small-molecule drugs plus chemo in postoperative gastric cancer: Retrospective analysis via molecular markers

doi:10.4240/wjgs.122160

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World Journal of Gastrointestinal Surgery

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1948-9366

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Retrospective Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Oct 27, 2026; 18(10): 122160
Published online Oct 27, 2026. doi: 10.4240/wjgs.122160

Table 1 Basic characteristics of patients in both groups, n (%) or mean ± SD

Baseline characteristics	Recurrence group (n = 38)	Non-recurrence group (n = 98)	χ²/t	P value
Gender			0.039	0.843
Male	21 (55.26)	56 (57.14)
Female	17 (44.74)	42 (42.86)
Age (year)			7.742	0.005
≥ 60	26 (68.42)	41 (41.84)
< 60	12 (31.58)	57 (58.16)
BMI (kg/m²)	24.16 ± 1.75	23.94 ± 1.92	0.614	0.540
Differentiation			51.193	< 0.001
Poorly differentiated	27 (71.05)	10 (10.20)
Moderately-well differentiated	11 (28.95)	88 (89.80)
Primary tumor location			0.067	0.795
Antrum/cardia	20 (52.63)	54 (55.10)
Body/fundus	18 (47.37)	44 (44.90)
TNM stage			26.668	< 0.001
III-IV	27 (71.05)	23 (23.47)
I-II	11 (28.95)	75 (76.53)
TCGA somatotype			0.434	0.664
EBV-positive type	17 (44.74)	46 (46.94)
Microsatellite unstable type	15 (39.47)	41 (41.84)
Genomic stable type	6 (15.79)	11 (11.22)

BMI: Body mass index; TCGA: The Cancer Genome Atlas; EBV: Epstein-Barr virus.

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Citation: Yang Y, Liu HD, Yang XY, Li X, Cui LJ. Recurrence risk prediction of small-molecule drugs plus chemo in postoperative gastric cancer: Retrospective analysis via molecular markers. World J Gastrointest Surg 2026; 18(10): 122160
URL: https://www.wjgnet.com/1948-9366/full/v18/i10/122160.htm
DOI: https://dx.doi.org/10.4240/wjgs.122160

Yang Y, Liu HD, Yang XY, Li X, Cui LJ. Recurrence risk prediction of small-molecule drugs plus chemo in postoperative gastric cancer: Retrospective analysis via molecular markers. World J Gastrointest Surg 2026; 18(10): 122160 [DOI: 10.4240/wjgs.122160]

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