Prognostic factors analysis of ultrasound-guided percutaneous puncture drainage in severe acute pancreatitis with peripancreatic fluid collection

Table 4 Clinical outcomes stratified by drainage timing, n (%)/median (interquartile range)

Outcome	Early drainage ≤ 72 hours (n = 70)	Late drainage > 72 hours (n = 64)	OR/difference	P value
Clinical success rate	58 (82.9)	38 (59.4)	3.32 (1.47-7.50)	0.004
ICU stay (days)	8.4 (5.2-12.6)	14.8 (9.6-22.4)	-6.4	< 0.001
Total hospital stay (days)	24.6 (18.4-32.8)	36.8 (28.6-48.4)	-12.2	< 0.001
Organ failure resolution at 7 days	44 (62.9)	24 (37.5)	2.82 (1.38-5.76)	0.004
Need for additional drainage	14 (20.0)	26 (40.6)	0.37 (0.17-0.81)	0.013
Progression to surgical intervention	6 (8.6)	18 (28.1)	0.24 (0.09-0.67)	0.006
In-hospital mortality	4 (5.7)	14 (21.9)	0.22 (0.07-0.71)	0.011

Early drainage: ≤ 72 hours from diagnosis to first percutaneous drainage. Late drainage: > 72 hours from diagnosis. OR: Odds ratio; ICU: Intensive care unit.