Risk factors analysis and management strategy optimization for postoperative complications in neonatal necrotizing enterocolitis: A single-center retrospective study

Table 2 Multivariate logistic regression analysis of factors associated with postoperative complications of neonatal necrotizing enterocolitis

Variable	β	SE	Wald χ2	P value	OR (95%CI)
Gestational age < 32 weeks	0.922	0.586	2.517	0.113	2.51 (0.81-7.79)
Birth weight < 1500 g	1.054	0.602	3.065	0.080	2.86 (0.88-9.28)
Preoperative mechanical ventilation required	0.883	0.627	2.013	0.156	2.41 (0.72-8.10)
Preoperative hemodynamic instability	1.675	0.558	9.234	0.002	5.32 (1.84-15.39)
Preoperative platelet count < 100 × 109/L	0.767	0.563	1.843	0.175	2.14 (0.72-6.38)
Preoperative blood lactate > 3.5 mmol/L	0.826	0.575	2.076	0.150	2.27 (0.74-6.96)
Time to surgery > 48 hours	0.698	0.591	1.372	0.242	1.99 (0.63-6.31)
Surgical procedure (stoma vs anastomosis)	0.543	0.586	0.863	0.354	1.72 (0.55-5.36)
Length of bowel resection > 30 cm	1.434	0.524	7.561	0.006	4.18 (1.51-11.56)
Postoperative mechanical ventilation > 7 days	1.180	0.503	5.564	0.019	3.25 (1.21-8.74)
Postoperative vasoactive drug use > 3 days	0.611	0.541	1.285	0.258	1.84 (0.64-5.29)
Serum albumin on postoperative day 3 < 30 g/L	1.339	0.512	6.805	0.008	3.77 (1.42-10.00)
Time to initiation of enteral nutrition > 7 days	0.725	0.557	1.718	0.191	2.05 (0.70-6.02)
Time to full enteral nutrition > 21 days	0.854	0.568	2.307	0.129	2.34 (0.78-7.02)
Postoperative hospital stay > 40 days	1.023	0.605	2.892	0.089	2.77 (0.86-8.94)
Constant	-2.896	0.815	12.749	< 0.001	0.06

OR: Odds ratio; CI: Confidence interval.