Correlation between pathological response to neoadjuvant immunotherapy and long-term survival in locally advanced rectal cancer: A real-world study

doi:10.4240/wjgs.121168

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 18, Issue 10

This Article

(8)

(7)

(0)

(7)

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Journal Information of This Article

Publication Name

World Journal of Gastrointestinal Surgery

ISSN

1948-9366

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Oct 27, 2026; 18(10): 121168
Published online Oct 27, 2026. doi: 10.4240/wjgs.121168

Table 2 Comparison of pathological response rates among different treatment regimens, n (%)

Treatment regimen	Number of patients	pCR (TRG 0)	MPR (TRG 1)	Non-MPR (TRGs 2 and 3)	Overall pathological response rate (TRGs 0 and 1)	χ²	P value
Immunotherapy monotherapy	53	6 (11.3)	11 (20.8)	36 (67.9)	17 (32.1)	10.362	< 0.001
Combination immunotherapy	77	24 (31.2)	20 (25.9)	33 (42.9)	44 (57.1)
Total	130	30 (23.1)	31 (23.8)	69 (53.1)	61 (46.9)

pCR: Pathological complete response; TRG: Tumor regression grade; MPR: Major pathological response.

Full Size Table

Citation: Zhang K, Li ZJ. Correlation between pathological response to neoadjuvant immunotherapy and long-term survival in locally advanced rectal cancer: A real-world study. World J Gastrointest Surg 2026; 18(10): 121168
URL: https://www.wjgnet.com/1948-9366/full/v18/i10/121168.htm
DOI: https://dx.doi.org/10.4240/wjgs.121168

Zhang K, Li ZJ. Correlation between pathological response to neoadjuvant immunotherapy and long-term survival in locally advanced rectal cancer: A real-world study. World J Gastrointest Surg 2026; 18(10): 121168 [DOI: 10.4240/wjgs.121168]

All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.