Copyright: ©Author(s) 2026.
World J Gastrointest Surg. Oct 27, 2026; 18(10): 121006
Published online Oct 27, 2026. doi: 10.4240/wjgs.121006
Published online Oct 27, 2026. doi: 10.4240/wjgs.121006
Table 3 Multivariate logistic regression analysis of independent risk factors for anastomotic leakage
| Variable | β | SE | Wald χ² | OR | 95%CI | P value |
| BMI ≥ 25 kg/m² | 0.856 | 0.346 | 6.124 | 2.354 | 1.196-4.632 | 0.013 |
| Diabetes mellitus | 0.978 | 0.382 | 6.556 | 2.660 | 1.258-5.624 | 0.010 |
| Tumor location (rectum) | 0.892 | 0.362 | 6.084 | 2.440 | 1.198-4.970 | 0.014 |
| Neoadjuvant therapy | 0.782 | 0.378 | 4.282 | 2.186 | 1.042-4.584 | 0.039 |
| Preop albumin < 35 g/L | 0.986 | 0.378 | 6.804 | 2.680 | 1.278-5.620 | 0.009 |
| Operation time ≥ 180 minutes | 0.848 | 0.364 | 5.424 | 2.334 | 1.142-4.770 | 0.020 |
| Intraop blood loss ≥ 200 mL | 0.762 | 0.376 | 4.108 | 2.142 | 1.024-4.482 | 0.043 |
| Protective stoma | -0.908 | 0.428 | 4.498 | 0.403 | 0.174-0.932 | 0.034 |
- Citation: Wang Y, Wang T, Xu ZD, Wang SH, Chen FF. Risk factors for anastomotic leakage after radical colorectal cancer surgery and its impact on prognosis: Clinical education research. World J Gastrointest Surg 2026; 18(10): 121006
- URL: https://www.wjgnet.com/1948-9366/full/v18/i10/121006.htm
- DOI: https://dx.doi.org/10.4240/wjgs.121006