Risk factors for anastomotic leakage after radical colorectal cancer surgery and its impact on prognosis: Clinical education research

Table 2 Univariate logistic regression analysis of risk factors for anastomotic leakage

Variable	OR	95%CI	Wald χ²	P value
Age (≥ 65 years vs < 65 years)	1.248	0.632-2.464	0.538	0.463
Gender (male vs female)	1.136	0.562-2.296	0.102	0.749
BMI (≥ 25 kg/m² vs < 25 kg/m²)	2.762	1.268-6.016	6.872	0.009
Diabetes mellitus (yes vs no)	2.824	1.342-5.938	8.124	0.004
Hypertension (yes vs no)	1.384	0.682-2.810	0.824	0.364
Smoking (yes vs no)	1.678	0.802-3.512	1.896	0.168
ASA grade III-IV vs I-II	2.384	1.062-5.354	4.528	0.033
Tumor location (rectum vs colon)	2.402	1.046-5.516	4.286	0.038
TNM stage III vs I-II	1.288	0.582-2.852	0.484	0.487
Neoadjuvant therapy (yes vs no)	2.152	0.928-4.994	3.162	0.075
Protective stoma (yes vs no)	0.468	0.166-1.322	2.286	0.043
Preop albumin < 35 g/L (yes vs no)	2.826	1.224-6.522	6.172	0.013
Operation time ≥ 180 minutes (yes vs no)	2.648	1.164-6.022	5.528	0.019
Intraop blood loss ≥ 200 mL (yes vs no)	2.284	1.006-5.186	3.928	0.048

BMI: Body mass index; ASA: American Society of Anesthesiologists; OR: Odds ratio.