Diagnostic value of interleukin-8 in colon cancer: Prospective, case-control study

Table 1 Univariate comparison of clinical and laboratory variables, mean ± SD

	Study group	Control group	P value
CEA (μg/L), median (IQR)	1.80 (1.00-5.05)	1.05 (0.65-1.44)	< 0.0011
IL-8 (ng/L), median (IQR)	53.88 (35.25-65.53)	34.93 (27.33-54.81)	0.0051
CRP (mg/L), median (IQR)	0.1 (0.10-0.50)	0.2 (0.20-0.60)	0.1391
Hemoglobin (g/dL)	12.35 ± 2.37	12.41 ± 2.14	0.903
WBC (× 109/L)	9.49 ± 3.85	9.72 ± 4.01	0.838
Platelet (× 109/L)	317.45 ± 106.53	270.86 ± 77.24	0.0211
AST (IU/L), median (IQR)	20 (19-29)	20 (16-31)	0.613
ALT (IU/L), median (IQR)	18 (14-29)	24 (18-34)	0.0191
Albumin (g/L), median (IQR)	41.0 (34.5-44.0)	40.0 (33.5-45.0)	0.930
Urea (mg/dL), median (IQR)	33 (25-48)	34 (26-45)	0.776
Creatinine (mg/dL), median (IQR)	0.88 (0.73-1.08)	0.76 (0.63-0.96)	0.0321
Potassium (mmol/L)	4.02 ± 0.51	4.09 ± 0.49	0.536
Hypertension (%)	22.7	43.2	0.0411
Diabetes mellitus (%)	11.4	22.7	0.1561
COPD (%)	9.1	2.3	0.360

¹Variables with P values below 0.2 were included in the multivariate analysis.

CEA: Carcinoembryonic antigen; IQR: Interquartile range; IL-8: Interleukin-8; CRP: C-reactive protein; WBC: White blood cell count; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; COPD: Chronic obstructive pulmonary disease.