Assessing predictive value of contrast-enhanced ultrasound combined with doppler ultrasound for post-transcatheter arterial chemoembolization prognosis in hepatocellular carcinoma

Table 1 Comparison of clinical data, contrast-enhanced ultrasound parameters, and Doppler ultrasound parameters between the two groups, n (%)/mean ± SD

Clinical data	Good prognosis group (n = 86)	Poor prognosis group (n = 38)	t/χ2	P value
Sex (male/female)	57/29	22/16	0.801	0.371
Age (years)	62.52 ± 5.24	63.82 ± 6.63	1.165	0.246
Body mass index (kg/m2)	23.48 ± 2.37	23.39 ± 2.41	0.194	0.846
TNM stage			5.684	0.017
I and II stage	58 (67.44)	17 (44.74)
III and IV stage	28 (32.56)	21 (5.26)
Child-Pugh classification
Grade A	53 (61.63)	2 (52.63)	0.881	0.348
Grade B	33 (38.37)	18 (47.37)
Tumor size			8.570	0.003
> 5 cm	30 (34.88)	24 (63.16)
≤ 5 cm	56 (65.12)	14 (36.84)
Number of lesions			5.725	0.017
Single	64 (74.42)	20 (52.63)
Multiple	22 (25.58)	18 (47.3)
Number of transcatheter arterial chemoembolization procedures (times)	2.06 ± 0.67	2.29 ± 0.73	1.715	0.089
Arrival time (seconds)	12.47 ± 1.82	11.20 ± 1.62	3.699	< 0.001
Time to peak (seconds)	25.29 ± 3.65	24.54 ± 3.78	1.042	0.299
Washout time (seconds)	79.44 ± 16.32	64.13 ± 14.58	4.971	< 0.001
Baseline intensity (dB)	4.13 ± 1.27	4.36 ± 1.32	0.917	0.361
Peak intensity (dB)	33.29 ± 5.63	33.87 ± 5.76	0.525	0.601
Hepatic artery peak systolic velocity (cm/second)	113.54 ± 18.68	135.28 ± 19.53	5.892	< 0.001
Portal vein velocity (cm/second)	14.38 ± 2.17	12.16 ± 1.67	5.612	< 0.001
Resistance index	0.82 ± 0.24	0.86 ± 0.27	0.805	0.422
Blood flow grading			8.839	0.032
Grade 0	6 (6.98)	1 (2.63)
Grade I	35 (40.70)	7 (18.42)
Grade II	26 (30.23)	14 (36.84)
Grade III	19 (22.09)	16 (42.11)