Preoperative clinical and laboratory factors associated with early complications after low anterior resection: Exploratory analysis of the eosinophil/lymphocyte ratio

Table 5 Comparisons of demographic and clinical data between the open low anterior resection surgery and laparoscopic low anterior resection surgery groups, n (%)

Variables	Open surgery group (n = 63)	Laparoscopic surgery group (n = 42)	P value
Age (years) (mean ± SD)	66.62 ± 12	65.45 ± 9.9	0.62
Gender, female/male	19/44 (30.2/69.8)	20/22 (47.6/52.4)	0.07
Diabetes mellitus	19 (30.2)	6 (14.3)	0.06
Smoking	13 (20.6)	9 (21.4)	0.92
Body mass index (kg/m2, mean ± SD)	24.05 ± 2.3	24.36 ± 2.1	0.49
Operating time (minutes) (mean ± SD)	274.13 ± 59	286.55 ± 57	0.29
Length of hospital stay (days) (mean ± SD)	10.97 ± 5.2	8.64 ± 2.9	0.011
Follow-up period (months) (mean ± SD)	48.83 ± 25	42.86 ± 25	0.24
Disease-free survival (months) (mean ± SD)	43.83 ± 26	40.48 ± 22	0.50
Removed LAP count (mean ± SD)	16.48 ± 6.4	16.98 ± 7.3	0.71
Metastasis LAP count (mean ± SD)	1.89 ± 2.9	1.12 ± 2.5	0.17
Stage classification			0.05
Stage 0	0 (0)	1 (2.4)
Stage 1	13 (20.6)	13 (31)
Stage 2	16 (25.4)	16 (38.1)
Stage 3	34 (54)	12 (28.6)
Mass localization level			0.65
Lower	8 (12.7)	6 (14.3)
Middle	17 (27)	8 (19)
Upper	38 (60.3)	28 (66.7)
Protective loop ileostomy	12 (19)	11 (26.2)	0.38
Neoadjuvant chemoradiotherapy	13 (20.6)	13 (31)
Preoperative albumin (g/L) (mean ± SD)	31.4 ± 5.6	32.6 ± 4.4	0.25
Hemoglobin (g/dL)
Preoperative (mean ± SD)	11.42 ± 2.1	11.62 ± 1.8	0.61
Postoperative day 1 (mean ± SD)	10.93 ± 1.2	10.55 ± 1.1	0.92
Neutrophil/Lymphocyte ratio
Preoperative (mean ± SD)	4.9 ± 2.6	5.8 ± 2.8	0.09
Postoperative day 1 (mean ± SD)	10.6 ± 3.8	10.7 ± 5.7	0.96
Postoperative day 3 (mean ± SD)	8.3 ± 4.1	7.8 ± 3.8	0.49
Eosinophil/Lymphocyte ratio
Preoperative (mean ± SD)	0.12 ± 0.1	0.14 ± 0.01	0.52
Postoperative day 1 (mean ± SD)	0.006 ± 0.01	0.954 ± 0.22	0.003
Postoperative day 3 (mean ± SD)	0.11 ± 0.1	0.24 ± 0.2	0.003
Lymphocyte/monocyte ratio
Preoperative (mean ± SD)	3.4 ± 1.7	2.7 ± 1.2	0.016
Postoperative day 1 (mean ± SD)	2.1 ± 1.6	1.6 ± 0.5	0.08
Postoperative day 3 (mean ± SD)	2.4 ± 0.8	2.3 ± 0.8	0.52
Prognostic nutritional index score (mean ± SD)	38.44 ± 6.8	38.84 ± 5.3	0.75
Early complications	23 (36.5)	6 (14.3)	0.01
Late complications			0.87
None	54 (85.7)	37 (88.1)
Bridge ileus	1 (1.6)	0 (0)
Anastomosis narrowing	5 (7.9)	3 (7.1)
Recurrence	3 (4.8)	2 (4.8)
Disease course			0.02
Remission	40 (63.5)	36 (85.7)
Progression	9 (14.3)	4 (9.5)
Mortality	14 (22.2)	2 (4.8)

LAP: Lymphadenopathy.