Differences in testosterone levels in perianal diseases: A comparative study of abscesses and fistulas

Table 6 Univariate analysis between disease characteristics and testosterone levels in the patients with anal fistula (n = 121)

Grouping category	n (%)	T (nmol/L), mean ± SD or median (P25, P75)	Mean/median diff (95%CI)	Test statistic	P value
Diabetes mellitus
No	103 (85.1)	12.30 (9.25, 16.60)	Reference	0.328	0.743
Yes	18 (14.9)	12.95 (9.93, 16.15)	-0.41 (-3.05 to 2.10)
Hypertension
No	105 (86.8)	13.37 ± 5.33	Reference	1.631	0.105
Yes	16 (13.2)	11.02 ± 4.17	2.34 (-0.50 to 5.19)
BMI (kg/m2)
≤ 24	44 (36.4)	15.84 ± 4.88	Reference	4.766	0.001
> 24	77 (63.6)	11.45 ± 4.80	4.35 (2.54-6.16)
Type of anal fistula
Trans sphincteric	84 (69.4)	13.25 ± 5.23	Reference	8.897	0.064
Inter sphincteric	17 (14)	13.09 ± 6.07	0.16 (-3.78 to 4.10)
Supra sphincteric	8 (6.6)	14.62 ± 4.65	-1.37 (-6.85 to 4.11)
Extra sphincteric	10 (8.3)	9.43 ± 3.23	3.82 (-1.13 to 8.77)
Submucosal	2 (1.7)	17.75 ± 1.63	-4.50 (-15.10 to 6.10)
Internal opening above the dentate line
No	112 (92.6)	13.42 ± 5.27	Reference	4.460	0.001
Yes	9 (7.4)	8.81 ± 2.72	4.61 (2.38-6.84)
Number of fistula tracts
< 2	97 (80.2)	12.97 ± 5.17	Reference	-0.462	0.645
≥ 2	24 (19.8)	13.52 ± 5.65	-0.55 (-2.93 to 1.82)
Intestinal inflammatory manifestations (n = 73)
No	55 (75.3)	11.7 (9.25, 15.30)	Reference	-0.557	0.578
Yes	18 (24.7)	13.10 (8.13, 16.00)	-0.07 (-3.40 to 2.10)

T: Testosterone; 95%CI: 95% confidence interval; BMI: Body mass index.