Clinical features of post-colonoscopy colorectal cancer and real-world multi-scale correlation analysis

Table 1 Baseline characteristics, n (%)

Characteristic	Confirmed diagnosis	Non-PCCRC	PCCRC	P value
Sex				0.3551
Male	3306 (61.85)	20 (74.07)	26 (66.67)
Female	2039 (38.15)	7 (25.93)	13 (33.33)
Age				0.0081
< 60	2523 (47.20)	18 (66.67)	11 (28.21)
≥ 60	2822 (52.80)	9 (33.33)	28 (71.79)
Location				< 0.0012
Ileocecal region	130 (2.43)	1 (3.70)	4 (10.26)
Ascending colon	314 (5.87)	1 (3.70)	3 (7.69)
Hepatic flexure	125 (2.34)	1 (3.70)	0 (0.00)
Transverse colon	122 (2.28)	4 (14.81)	1 (2.56)
Splenic flexure	21 (0.39)	0 (0.00)	0 (0.00)
Descending colon	197 (3.69)	3 (11.11)	4 (10.26)
Sigmoid colon	1266 (23.69)	6 (22.22)	12 (30.77)
Rectum	3108 (58.15)	10 (37.04)	7 (17.95)
Anastomotic site	62 (1.16)	1 (3.70)	8 (20.51)
Sedation				0.0461
Present	3019 (56.48)	18 (66.67)	29 (74.36)
Absent	2326 (43.52)	9 (33.33)	10 (25.64)
Bowl preparation				0.0042
Excellent	590 (11.04)	0 (0.00)	1 (2.56)
Good	2118 (39.63)	14 (51.85)	15 (38.46)
Inadequate	927 (17.34)	11 (40.74)	9 (23.08)
Poor	1015 (18.99)	2 (7.41)	11 (28.21)
Unclear	695 (13.00)	0 (0.00)	3 (7.69)
Adenoma3				0.7741
Present	1264 (65.12)	15 (60.00)	12 (70.59)
Absent	677 (34.88)	10 (40.00)	5 (29.41)

¹Pearson’s χ² test.

²Simulated P value.

³n was calculated as the total number of endoscopic procedures performed (n = 5411), while n was calculated based on the number of unique patients (n = 2047).

PCCRC: Post-colonoscopy colorectal cancer.