Risk factors for enteral nutrition intolerance and its impact on prognosis in patients with severe acute pancreatitis

doi:10.4240/wjgs.v18.i1.112334

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Surg. Jan 27, 2026; 18(1): 112334
Published online Jan 27, 2026. doi: 10.4240/wjgs.v18.i1.112334

Table 9 Cox regression analysis of factors affecting 28-day mortality

Variables	β	SE	Wald χ²	P value	HR	95%CI
Enteral nutrition intolerance	0.771	0.333	5.366	0.020	2.164	1.127-4.156
APACHE II score	0.083	0.031	7.305	0.007	1.086	1.023-1.153
Number of organ failures	0.485	0.162	8.954	0.003	1.624	1.186-2.225

Cox regression model concordance index = 0.778 (95% confidence interval: 0.701-0.855); Bootstrap validation concordance index = 0.765 (95% confidence interval: 0.698-0.832); proportional hazards assumption test P = 0.276. HR: Hazard ratio; CI: Confidence interval; APACHE: Acute Physiology and Chronic Health Evaluation.

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Citation: Wu CM, Zhu WJ, Chen X, Liu M, Feng Y, Wang M. Risk factors for enteral nutrition intolerance and its impact on prognosis in patients with severe acute pancreatitis. World J Gastrointest Surg 2026; 18(1): 112334
URL: https://www.wjgnet.com/1948-9366/full/v18/i1/112334.htm
DOI: https://dx.doi.org/10.4240/wjgs.v18.i1.112334

Wu CM, Zhu WJ, Chen X, Liu M, Feng Y, Wang M. Risk factors for enteral nutrition intolerance and its impact on prognosis in patients with severe acute pancreatitis. World J Gastrointest Surg 2026; 18(1): 112334 [PMID: 41695844 DOI: 10.4240/wjgs.v18.i1.112334]

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