Risk factors for enteral nutrition intolerance and its impact on prognosis in patients with severe acute pancreatitis

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

World J Gastrointest Surg. Jan 27, 2026; 18(1): 112334
Published online Jan 27, 2026. doi: 10.4240/wjgs.v18.i1.112334

Table 5 Comparison of treatment measures between two groups, n (%)

Indicators	Intolerance group (n = 76)	Tolerance group (n = 119)	Test statistic	P value
Respiratory support
Mechanical ventilation	68 (89.5)	88 (73.9)	6.298	0.012
PEEP (cmH₂O), mean ± SD	8.4 ± 2.6	7.2 ± 2.1	3.468	0.001
FiO₂ (%), mean ± SD	52.4 ± 18.2	42.8 ± 14.6	4.227	< 0.001
Circulatory support
Vasoactive drug use	60 (78.9)	70 (58.8)	7.941	0.005
Vasoactive drug duration (day), mean ± SD	8.6 ± 4.2	5.9 ± 3.1	4.873	< 0.001
Gastrointestinal therapy
Gastrointestinal motility drug use	68 (89.5)	70 (58.8)	19.586	< 0.001
Other therapies
Antibiotic therapy duration (day), mean ± SD	14.8 ± 6.2	11.2 ± 4.8	4.284	< 0.001
Continuous renal replacement therapy	32 (42.1)	31 (26.1)	5.259	0.022
Surgical intervention	28 (36.8)	31 (26.1)	2.472	0.116

PEEP: Positive end expiratory pressure.

Citation: Wu CM, Zhu WJ, Chen X, Liu M, Feng Y, Wang M. Risk factors for enteral nutrition intolerance and its impact on prognosis in patients with severe acute pancreatitis. World J Gastrointest Surg 2026; 18(1): 112334
URL: https://www.wjgnet.com/1948-9366/full/v18/i1/112334.htm
DOI: https://dx.doi.org/10.4240/wjgs.v18.i1.112334

Wu CM, Zhu WJ, Chen X, Liu M, Feng Y, Wang M. Risk factors for enteral nutrition intolerance and its impact on prognosis in patients with severe acute pancreatitis. World J Gastrointest Surg 2026; 18(1): 112334 [PMID: 41695844 DOI: 10.4240/wjgs.v18.i1.112334]

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