Remimazolam reduces State-Trait Anxiety Inventory-State Scale scores in hemorrhoid surgery with spinal-epidural anesthesia: A randomized trial

Table 4 Comparison of Ramsay sedation scores at different postoperative time points

Time point	CSE group, n = 30	Combined group, n = 30	Median difference (95%CI)	P value
T0	2.00 (2.00-2.00)	2.00 (2.00-2.00)	0.00 (0.00-0.00)	0.492
T1	2.00 (2.00-2.00)	2.00 (2.00-2.00)	0.00 (0.00-0.00)	0.492
T2	2.00 (2.00-2.00)	5.00 (5.00-5.00)	3.00 (3.00-3.00)	< 0.001a
T3	2.00 (2.00-2.00)	5.00 (5.00-5.00)	3.00 (3.00-3.00)	< 0.001a
T4	2.00 (2.00-2.00)	2.00 (2.00-2.00)	0.00 (0.00-0.00)	> 0.999

^aP < 0.05.

P values were calculated using the Mann-Whitney U test, with Hodges-Lehmann estimated median differences (95%CI). T1 was the time prior to positioning. T2 was the time at the commencement of surgery. T3 was 10 minutes after the start of the surgical procedure. T4 was the time when patients were discharged from the operating room. CSE: Combined spinal-epidural.