Diagnostic significance of fluorine-18-fluorodeoxyglucose-positron emission tomography/computed tomography in differentiating Edmondson grade II and III hepatocellular carcinoma

Figure 1 Hepatocellular carcinoma in the right hepatic lobe, with an Edmondson grade of III (Case 1). The percentage of Ki67 expression was 30%, maximum standardized uptake value was 15.56, mean standardized uptake value was 6.24, metabolic tumor volume was 94.7, total lesion glycolysis was 590.5, tumor-to-normal background ratio was 5.02, and tumor-to-blood pool ratio was 8.64. A: Non-enhanced computerized tomography image depicted a slightly hypodense mass (blue arrow) beneath the capsule of the right hepatic lobe, with an approximate computerized tomography value of 32 Hounsfield unit, a three-dimensional volume of interest was manually outlined along the tumor periphery; B: Normal liver tissue region of interest (white arrow) and abdominal aorta region of interest (green arrow); C: Axial maximum intensity projection image; D: Coronal view; E: Sagittal view; F: Sagittal maximum intensity projection image. PT: Positron tomography; CT: Computed tomography; 3D: Three-dimensional.