Preoperative performance status was associated with postoperative fatal complications in elderly patients with refractory ulcerative colitis

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World Journal of Gastrointestinal Surgery

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1948-9366

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World J Gastrointest Surg. Aug 27, 2025; 17(8): 109326
Published online Aug 27, 2025. doi: 10.4240/wjgs.v17.i8.109326

Table 3 Logistic regression analysis of risk factors for fatal complications¹

Factors	Univariate analysis		Multivariate analysis
Factors	OR (95%CI)	P value	OR (95%CI)	P value
Age at surgery (1-year intervals)	1.05 (0.99-1.12)	0.09	1.01 (0.93-1.10)	0.76
Severe disease	3.30 (1.04-10.43)	0.04^b	1.10 (0.22-5.34)	0.90
BMI < 17	3.11 (1.16-8.37)	0.01^b	4.08 (1.19-13.97)	0.02^b
Preoperative PSL	2.45 (0.83-7.18)	0.09	3.67 (0.92-14.60)	0.05
Immunomodulators	0.29 (0.09-0.93)	0.02^b	0.41 (0.10-1.60)	0.18
Urgent/emergent surgery	6.53 (1.82-23.39)	< 0.01^b	1.61 (0.28-9.15)	0.58
Performance status ≥ 3	15.42 (4.75-49.96)	< 0.01^b	14.5 (3.43-61.64)	< 0.01^b
Lymphocyte count (1/μL intervals)	0.99 (0.99-1.00)	0.04^b	1.00 (0.99-1.00)	0.56
Carlson risk index ≥ 3	3.22 (0.93-11.12)	0.05	1.74 (0.37-8.17)	0.48

¹Fatal complications include life-threatening complications requiring ICU management and the death of a patient.

^bP < 0.05 (significant difference).

OR: Odds ratio; 95%CI: 95% confidence interval; Alb: Albumin; ASA: American Society of Anesthesiologists; BMI: Body mass index; PSL: Prednisolone.

Citation: Horio Y, Uchino M, Tomoo Y, Nomura K, Nagano K, Kusunoki K, Kuwahara R, Kimura K, Sato T, Kataoka K, Igeta M, Shinzaki S, Ikeda M, Ikeuchi H. Preoperative performance status was associated with postoperative fatal complications in elderly patients with refractory ulcerative colitis. World J Gastrointest Surg 2025; 17(8): 109326
URL: https://www.wjgnet.com/1948-9366/full/v17/i8/109326.htm
DOI: https://dx.doi.org/10.4240/wjgs.v17.i8.109326

Horio Y, Uchino M, Tomoo Y, Nomura K, Nagano K, Kusunoki K, Kuwahara R, Kimura K, Sato T, Kataoka K, Igeta M, Shinzaki S, Ikeda M, Ikeuchi H. Preoperative performance status was associated with postoperative fatal complications in elderly patients with refractory ulcerative colitis. World J Gastrointest Surg 2025; 17(8): 109326 [PMID: 40949376 DOI: 10.4240/wjgs.v17.i8.109326]

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