Preoperative performance status was associated with postoperative fatal complications in elderly patients with refractory ulcerative colitis

doi:10.4240/wjgs.v17.i8.109326

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 17, Issue 8

This Article

(57)

(60)

(0)

(9)

(1896)

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Journal Information of This Article

Publication Name

World Journal of Gastrointestinal Surgery

ISSN

1948-9366

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

World J Gastrointest Surg. Aug 27, 2025; 17(8): 109326
Published online Aug 27, 2025. doi: 10.4240/wjgs.v17.i8.109326

Table 2 Patient characteristics

	All elderly patients, n = 191	Fatal complication group¹, n = 18	Non-fatal complication group, n = 173	P value
Sex, male/female	131/60	15/3	116/57	0.15
Age at surgery (years)	70.8 ± 7.5	73.7 ± 8.4	70.5 ± 7.3	0.09
Elderly onset	139 (72.7)	16 (88.8)	123 (71.0)	0.10
Disease duration (months)	28 (6-103)	9 (3.75-64)	30 (7-104)	0.48
Severe disease	103 (53.9)	14 (77.7)	89 (51.4)	0.04^b
Alb (g/dL)	2.6 (2.1-3.2)	2.2 (1.7-2.7)	2.6 (2.1-3.2)	0.15
Lymphocyte (count/μL)	1114 (543-1668)	688 (204-1544)	1164 (564-1684)	0.06
CRP (mg/dL)	1.7 (0.2-5.7)	3.3 (0.7-8.5)	1.5 (0.2-5.5)	0.11
BMI	18.8 (16.6-21.4)	16.8 (15.0-19.5)	18.8 (17.0-21.4)	0.02^b
Performance status ≥ 3	46 (24.0)	14 (77.7)	32 (18.4)	< 0.01^b
Smoker	32 (16.7)	1 (5.5)	31 (17.9)	0.18
ASA-PS ≥ 3	90 (47.1)	13 (72.2)	77 (44.5)	0.06
Carlson risk index ≥ 3	18 (9.4)	4 (22.2)	14 (8.0)	0.05
Pharmacotherapy
Total given PSL dose (mg)	2000 (500-6260)	1840 (1176-5150)	2000 (500-6610)	0.55
Preoperative PSL	102 (53.4)	13 (72.2)	89 (51.4)	0.09
Immunomodulators	89 (46.5)	4 (22.2)	85 (49.1)	0.02^b
Calcineurin inhibitors	18 (9.4)	2 (11.1)	16 (9.2)	0.16
JAK inhibitors	3 (1.5)	0 (0)	3 (1.7)	0.57
Biologics	60 (31.4)	5 (27.7)	55 (31.7)	0.72
Urgent/emergent surgery	90 (47.1)	15 (83.3)	75 (43.3)	< 0.01^b
Laparoscopic surgery	47 (24.6)	4 (22.2)	43 (24.8)	0.80
Operative time (minutes)	202 (163-253)	173 (122-193)	207 (172-262)	< 0.01^b
TC with ileostomy	96 (50.2)	12 (66.6)	84 (48.5)	0.14
APR with ileostomy	47 (24.6)	1 (5.5)	46 (26.5)	0.04^b
Pouch surgery	58 (30.3)	3 (16.6)	55 (31.7)	0.18
Blood loss (mL)	170 (75-300)	100 (27-196)	180 (80-310)	0.73
Blood transfusion	90 (47.1)	10 (55.5)	80 (46.2)	0.45

¹Fatal complications include life-threatening complications requiring intensive care unit management and the death of a patient.

^bP < 0.05 (significantly different).

Data are presented as numbers with percentages in parentheses unless otherwise indicated. Continuous variables are indicated as the mean ± SD and median (quartile range). UC: Ulcerative colitis; PSL: Prednisolone; CRP: C reactive protein; Alb: Albumin; BMI: Body mass index; ASA: American Society of Anesthesiologists; TC: Total colectomy; APR: Abdominal perineal resection.

Full Size Table

Citation: Horio Y, Uchino M, Tomoo Y, Nomura K, Nagano K, Kusunoki K, Kuwahara R, Kimura K, Sato T, Kataoka K, Igeta M, Shinzaki S, Ikeda M, Ikeuchi H. Preoperative performance status was associated with postoperative fatal complications in elderly patients with refractory ulcerative colitis. World J Gastrointest Surg 2025; 17(8): 109326
URL: https://www.wjgnet.com/1948-9366/full/v17/i8/109326.htm
DOI: https://dx.doi.org/10.4240/wjgs.v17.i8.109326

Horio Y, Uchino M, Tomoo Y, Nomura K, Nagano K, Kusunoki K, Kuwahara R, Kimura K, Sato T, Kataoka K, Igeta M, Shinzaki S, Ikeda M, Ikeuchi H. Preoperative performance status was associated with postoperative fatal complications in elderly patients with refractory ulcerative colitis. World J Gastrointest Surg 2025; 17(8): 109326 [PMID: 40949376 DOI: 10.4240/wjgs.v17.i8.109326]

All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.