Correlation between laparoscopic radical resection and tumor markers in peritoneal irrigation fluid

Table 14 Association between simultaneous cancer leakage of carcinoembryonic antigen and cytokeratin-19 markers and clinicopathological characteristics of patients, n (%)

Variable	Total (n = 115)	CEA and CK-19 - (n = 103)	CEA and CK-19 + (n = 12)	Statistic	P value
Number of positive lymph nodes, median (Q1, Q3)	3.00 (0.00, 9.50)	2.00 (0.00, 8.00)	9.50 (6.25, 21.25)	Z = 2.948	0.004
Degree of differentiation				χ2 = 4.462	0.035
Low	68 (59.13)	57 (55.34)	11 (91.67)
Medium-high	47 (40.87)	46 (44.66)	1 (8.33)
T grade					0.006
T1	21 (18.26)	21 (20.39)	0 (0.00)
T2	13 (11.3)	12 (11.65)	1 (8.33)
T3	46 (40)	44 (42.72)	2 (16.67)
T4	35 (30.43)	26 (25.24)	9 (75.00)
N grade					0.027
N0	37 (32.17)	36 (34.95)	1 (8.33)
N1	16 (13.91)	16 (15.53)	0 (0.00)
N2	19 (16.52)	17 (16.50)	2 (16.67)
N3	43 (37.39)	34 (33.01)	9 (75.00)
TNM grade					0.022
I	29 (25.22)	28 (27.18)	1 (8.33)
II	23 (20)	23 (22.33)	0 (0.00)
III	63 (54.78)	52 (50.49)	11 (91.67)
Modus operandi				χ2 = 6.112	0.013
Membrane anatomy	58 (50.43)	56 (54.37)	2 (16.67)
D2	57 (49.57)	47 (45.63)	10 (83.33)

TNM: Tumor node metastasis; CEA: Carcinoembryonic antigen; CK-19: Cytokeratin-19.