Observational Study
Copyright ©The Author(s) 2025.
World J Gastrointest Surg. Aug 27, 2025; 17(8): 104568
Published online Aug 27, 2025. doi: 10.4240/wjgs.v17.i8.104568
Table 1 Baseline characteristics of the study population
Characteristic
n (%)
Sex
Male45 (60)
Female30 (40)
Age, years58 (35-75)
Primary tumor location
Colon40 (53.3)
Rectum35 (46.7)
Initial AJCC stage
Stage III20 (26.7)
Stage IV55 (73.3)
Disease-free interval, months24 (6-60)
Liver metastases
Solitary30 (40)
Multiple45 (60)
Number of metastases3 (1-10)
Average size of metastases, cm4.5 ± 1.8
Location of metastases
Right lobe41 (55)
Left lobe23 (30)
Both lobes11 (15)
Molecular profiling
KRAS mutation35 (46.7)
NRAS mutation15 (20)
Wild-type RAS25 (33.3)
VEGF overexpression50 (66.7)
EGFR expression40 (53.3)
Prior treatments
Systemic chemotherapy20 (26.7)
Targeted therapy10 (13.3)