Genetically engineered mouse models in gastric precancerous lesions research

Figure 2 Working principle of cyclization recombinase/locus of X-over P1 system. The figures were created using the Figdraw platform. Cyclization recombinase recombinase cuts the DNA at the locus of X-over P1 sites and then recombines the remaining DNA, ultimately resulting in the deletion of the target gene between the locus of X-over P1 sites. LoxP: Locus of X-over P1; Cre: Cyclization recombinase.