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World J Gastrointest Surg. Jul 27, 2025; 17(7): 107385
Published online Jul 27, 2025. doi: 10.4240/wjgs.v17.i7.107385
Table 1 Overview of key aspects related to endoscopic retrograde cholangiopancreatography and its complications, including types, risk factors, clinical presentation, diagnostic approach, management strategies, and prognosis

Key points
IntroductionERCP is a valuable but high-risk procedure, mainly for therapeutic purposes (e.g., bile duct stone extraction, stent placement)
Complication typesIncludes pancreatitis (most common), bleeding (intraprocedural or postprocedural), perforation (duodenal, biliary tract), infection (cholangitis, cholecystitis, liver abscess), cardiopulmonary complications, post-sphincterotomy bleeding, perforation by stent migration, Dormia basket impaction
Risk factorsPatient-related (e.g., young age, sphincter of Oddi dysfunction), procedure-related (e.g., difficult cannulation, multiple attempts)
Clinical presentationVaries by complication: Abdominal pain, fever, jaundice, anemisation, hypotension, signs of peritonitis
Diagnostic approachImaging: Ultrasound, CT, MRCP. Lab tests: blood count, CRP and inflammatory markers, amylase/lipase, liver function tests
Management strategiesSupportive care (fluids, analgesia), antibiotics for infection, endoscopic management. For severe cases (e.g., perforation, large bile leaks) surgical intervention
PrognosisMost complications resolve with timely diagnosis and appropriate management. Severe cases require multidisciplinary care