Proton beam therapy for esophageal cancer compared to existing treatments, including X-ray therapy and surgery

Table 2 Clinical results of previous reports in which clinical data were reported in the text

Ref.	Modality	Definitive settings (%)	Number of patients	Median follow up (months)	OS (%)					PFS (%)
					1 year	1.5 years	2 years	3 years	5 years	1 years	2 years	3 years	5 years
Choi et al[25]	3DCRT	0	16	17.0	-	-	67.8	-	-	-	33.3	-	-
	PBT	0	15	17.0	-	-	68.6	-	-	-	34.5	-	-
Xi et al[28]	3DCRT	100	41	65.1	-	-		-	31.6	-	-	-	20.4
	PBT	100	132	44.8	-	-		-	41.6	-	-	-	34.9
Bhangoo et al[27]	IMRT	28	32	14	71	-	-	-	-	45	-	-	-
	PBT	19	32	10	74	-	-	-	-	71	-	-	-
Lin et al[30]	IMRT	50.8	61	44.1	-	-	-	50.8	-	-	-	44.8	-
	PBT	54.3	46	44.1	-	-	-	51.2	-	-	-	44.5	-
Sumiya et al[36]	3DCRT (all)	100	15	-	-	-	47.7	-	-	-	-	-	-
	PBT (all)	100	54	-	-	-	77.2	-	-		-	-	-
	3DCRT (≥ stage 2)	100	14	-	-	-	41.1	-	-	-	-	-	-
	PBT (≥ stage 2)	100	31	-	-	-	68.9	-	-		-	-	-
DeCesaris et al[40]	IMRT	0	36	-	-	59	-	-	-	-	-	-	-
	PBT	0	18	-	-	83	-	-	-	-	-	-	-

3DCRT: 3-dimetional conformal radiotherapy; IMRT: Intensity modulated radiotherapy; PBT: Proton beam therapy; PFS: Progression free survival; OS: Overall survival.