Copyright
©The Author(s) 2025.
World J Gastrointest Surg. Jul 27, 2025; 17(7): 106487
Published online Jul 27, 2025. doi: 10.4240/wjgs.v17.i7.106487
Published online Jul 27, 2025. doi: 10.4240/wjgs.v17.i7.106487
Table 3 Comparison of clinical data of patients with different curative effects
Characteristic | Total number of cases (n = 80) | Effective (n = 62) | Invalid (n = 18) | χ2/t | P value | |
Use Baohe Pingwei powder | 26 (32.50) | 24 (38.71) | 2 (11.11) | 4.843 | 0.029 | |
Age (mean ± SD, years) | 68.51 ± 1.94 | 68.67 ± 2.13 | 68.02 ± 2.04 | 1.150 | 0.254 | |
Gender | Male | 63 (78.75) | 50 (80.65) | 13 (72.22) | 0.195 | 0.659 |
Female | 17 (21.25) | 12 (19.35) | 5 (27.78) | |||
Tumor location | Gastric antrum or pylorus | 57 (71.25) | 45 (72.58) | 12 (66.67) | 0.456 | 0.648 |
Stomach body | 11 (13.75) | 8 (12.90) | 3 (16.67) | |||
Gastric fundus or cardia | 12 (15.00) | 9 (14.52) | 3 (16.67) | |||
Clinical staging | Phase II | 39 (48.75) | 31 (50.00) | 8 (44.44) | 0.172 | 0.678 |
Phase III | 41 (51.25) | 31 (50.00) | 10 (55.56) | |||
Surgical scope | Partial excision | 42 (52.50) | 33 (53.23) | 9 (50.00) | 0.058 | 0.809 |
Fully cut | 38 (47.50) | 29 (46.77) | 9 (50.00) | |||
Tumor size | < 2 cm | 15 (18.75) | 13 (20.97) | 2 (11.11) | 2.172 | 0.030 |
2-5 cm | 50 (62.50) | 41 (66.13) | 9 (50.00) | |||
> 5 cm | 15 (18.75) | 8 (12.90) | 7 (38.89) | |||
Degree of differentiation | High | 4 (5.00) | 2 (3.23) | 2 (11.11) | 2.675 | 0.008 |
In | 24 (30.00) | 15 (24.19) | 9 (50.00) | |||
Low | 52 (65.00) | 45 (72.58) | 7 (38.89) | |||
Smoke | Have | 33 (41.25) | 27 (43.55) | 6 (33.33) | 0.601 | 0.438 |
Without | 47 (58.75) | 35 (56.45) | 12 (66.67) | |||
Drink | Have | 55 (68.75) | 44 (70.97) | 11 (61.11) | 0.601 | 0.427 |
Without | 25 (31.25) | 18 (29.03) | 7 (38.89) | |||
Hypertension | Have | 36 (45.00) | 26 (41.94) | 10 (55.56) | 1.667 | 0.197 |
Without | 44 (55.00) | 37 (59.68) | 7 (38.89) | |||
Diabetes mellitus | Have | 30 (37.50) | 24 (38.71) | 6 (33.33) | 0.172 | 0.678 |
Without | 50 (62.50) | 38 (61.29) | 12 (66.67) | |||
CD3+ (mean ± SD, %) | Before treatment | 56.59 ± 1.67 | 57.36 ± 2.34 | 56.84 ± 2.01 | 0.0855 | 0.395 |
After treatment | 37.34 ± 1.58 | 45.67 ± 2.03 | 32.16 ± 1.35 | 26.521 | 0.000 | |
CD4+ (mean ± SD, %) | Before treatment | 39.46 ± 1.26 | 39.15 ± 2.06 | 40.12 ± 2.37 | 1.700 | 0.082 |
After treatment | 25.64 ± 1.03 | 30.58 ± 1.64 | 21.34 ± 1.42 | 21.642 | 0.000 | |
CA19-9 (mean ± SD, %) | Before treatment | 71.69 ± 2.45 | 71.64 ± 2.43 | 72.87 ± 2.16 | 1.935 | 0.057 |
After treatment | 36.98 ± 2.06 | 35.69 ± 1.26 | 38.59 ± 2.16 | 7.207 | 0.000 | |
CA242 (U/mL) | Before treatment | 44.27 ± 0.28 | 44.17 ± 0.25 | 44.15 ± 0.03 | 0.337 | 0.737 |
After treatment | 26.31 ± 1.34 | 37.12 ± 2.13 | 12.24 ± 0.15 | 49.299 | 0.000 | |
IL-6 (mean ± SD, ng/mL) | Before treatment | 428.94 ± 2.69 | 429.67 ± 2.16 | 429.32 ± 2.15 | 0.606 | 0.546 |
After treatment | 317.65 ± 2.36 | 310.84 ± 2.67 | 328.12 ± 2.37 | 24.751 | 0.000 | |
IL-10 (mean ± SD, ng/mL) | Before treatment | 92.84± 1.52 | 92.98 ± 1.76 | 92.48 ± 1.38 | 1.109 | 0.271 |
After treatment | 234.18 ± 2.68 | 61.08 ± 1.26 | 86.41 ± 1.28 | 74.824 | 0.000 | |
TNF-α (mean ± SD, ng/mL) | Before treatment | 321.23 ± 2.03 | 321.08 ± 0.99 | 321.54 ± 2.31 | 1.237 | 0.220 |
After treatment | 261.33 ± 2.07 | 220.09 ± 1.28 | 319.26 ± 2.17 | 243.829 | 0.000 |
- Citation: Ma HY, Liu X, Chen YW, Liang J, Wang J, Zhang MM, Yang Q. Baohe Pingwei power plus neoadjuvant chemotherapy for gastric cancer. World J Gastrointest Surg 2025; 17(7): 106487
- URL: https://www.wjgnet.com/1948-9366/full/v17/i7/106487.htm
- DOI: https://dx.doi.org/10.4240/wjgs.v17.i7.106487