Intestinal microbiota characteristics and dietary fiber intervention in patients undergoing endoscopic mucosa resection

Table 3 Molecular transformation of microbiota structure and functional genes, mean ± SD

Microbiota composition and gene expression indicators	Control group	Intervention group	P value
Beneficial bacterial populations
Lactobacilli abundance (%)	12.4 ± 2.1	18.6 ± 2.3	< 0.01
Bifidobacteria abundance (%)	8.7 ± 1.5	15.3 ± 1.8	< 0.01
Pathogenic bacterial populations
Gram-negative bacteria (%)	42.6 ± 3.2	28.4 ± 2.7	< 0.01
Conditional pathogenic bacteria (%)	24.3 ± 2.5	15.6 ± 2.1	< 0.01
Intestinal barrier-related gene expression
Tight junction proteins	0.68 ± 0.12	1.42 ± 0.16	< 0.01
Defensin genes	0.52 ± 0.09	1.27 ± 0.14	< 0.01
Microbial diversity indices
Microbial diversity index	0.36 ± 0.05	0.82 ± 0.07	< 0.01
Functional gene diversity	124 ± 18	212 ± 25	< 0.01
Metabolic function genes
Short-chain fatty acid production genes	36.5 ± 4.2	58.7 ± 5.1	< 0.01