Intestinal microbiota characteristics and dietary fiber intervention in patients undergoing endoscopic mucosa resection

Table 2 Dynamic changes in intestinal microbiota diversity following endoscopic mucosa resection, mean ± SD

Microbiota diversity indicators	Control group	Intervention group	P value
Baseline
Shannon diversity index	4.52 ± 0.33	4.52 ± 0.33	0.990
Bacterial species richness	245 ± 32	246 ± 33	0.985
Simpson index	0.85 ± 0.07	0.85 ± 0.07	0.995
Firmicutes/bacteroidetes ratio	1.20 ± 0.20	1.20 ± 0.20	0.995
Microbial stability score	1.00	1.00	-
Alpha diversity (observed species)	250 ± 35	250 ± 35	0.990
Chao1 richness estimator	260 ± 40	260 ± 40	0.990
ACE richness estimator	270 ± 45	270 ± 45	0.990
PD whole tree (phylogenetic diversity)	0.75 ± 0.08	0.75 ± 0.08	0.990
2 weeks post-surgery
Shannon diversity index	2.87 ± 0.25	3.76 ± 0.28	< 0.01
Bacterial species richness	178 ± 26	225 ± 30	< 0.01
Simpson index	0.60 ± 0.06	0.75 ± 0.06	< 0.01
Firmicutes/bacteroidetes ratio	0.80 ± 0.15	1.00 ± 0.18	< 0.01
Microbial stability score	0.62 ± 0.08	0.75 ± 0.07	< 0.01
Alpha diversity (observed species)	180 ± 25	230 ± 30	< 0.01
Chao1 richness estimator	190 ± 30	240 ± 35	< 0.01
ACE richness estimator	200 ± 35	250 ± 40	< 0.01
PD whole tree (phylogenetic diversity)	0.55 ± 0.07	0.65 ± 0.07	< 0.01
4 weeks post-surgery
Shannon diversity index	3.24 ± 0.31	4.41 ± 0.32	< 0.01
Bacterial species richness	203 ± 29	242 ± 31	< 0.01
Simpson index	0.70 ± 0.07	0.84 ± 0.07	< 0.01
Firmicutes/bacteroidetes ratio	0.90 ± 0.16	1.10 ± 0.20	< 0.01
Microbial stability score	0.95 ± 0.06	0.98 ± 0.05	< 0.01
Alpha diversity (observed species)	210 ± 30	245 ± 32	< 0.01
Chao1 richness estimator	220 ± 35	255 ± 38	< 0.01
ACE richness estimator	230 ± 40	265 ± 42	< 0.01
PD whole tree (phylogenetic diversity)	0.65 ± 0.08	0.72 ± 0.08	< 0.01

ACE: Abundance-based coverage estimator; PD: Phylogenetic diversity.