Observational Study
Copyright ©The Author(s) 2025.
World J Gastrointest Surg. Jul 27, 2025; 17(7): 105136
Published online Jul 27, 2025. doi: 10.4240/wjgs.v17.i7.105136
Figure 2
Figure 2 Endoscopic, ultrasonic endoscopic and pathological characteristics of gastric inflammatory fibroid polyps. A-F: Nodular stage; A: General endoscopic features: A submucosal protrusion on the anterior wall of the gastric antrum near the pylorus, with smooth and intact surface mucosa; B: Endoscopic ultrasonography (EUS) features: The lesion originated from the third layer, with low echo, homogeneous echo and indistinct margin; C: Pathological characteristics: Immature fibroblastic-like spindle cell proliferation, few inflammatory cells such as eosinophils, and a small amount of thin-walled vascular proliferation, hematoxylin-eosin (HE): 200 ×; D: Immunohistochemical cluster of differentiation (CD) 34 +: 200 ×; E: Immunohistochemical smooth muscle actin (SMA) +: 200 ×; F: Immunohistochemical vimentin +: 200 ×; G-L: Fibrovascular stage; G: General endoscopic features: A submucosal protrusion on the lesser curvature of the gastric antrum, with hyperemia of the surface mucosa; H: EUS features: Lesion originated from the second layer, with medium-low echo, homogeneous echo and indistinct margin; I: Pathological characteristics: Mature fibroblastic-like spindle cell proliferation, thin- and thick-walled blood vessels are visible, and there is a significant eosinophil proliferation around the blood vessels. The proliferating spindle cells exhibit a classic “onion skin” pattern around small blood vessels, HE: 200 ×; J: Immunohistochemical CD34 +: 200 ×; K: Immunohistochemical SMA +: 200 ×; L: Immunohistochemical vimentin + 200 ×.