Epidemiology, treatment patterns, and associated risk factors in perianal fistulizing Crohn’s disease: A systematic literature review

Figure 2 Proportions of patients with Crohn’s perianal fistulas receiving one of the top five most frequently reported interventions used as first, second, or third treatment within a study. Numbers in the key represent the number of studies reporting the intervention as the first, second, and/or third treatment in a study; some studies reported an intervention in more than one line of treatment. Numbers above the bars are median (interquartile range) proportion of patients; number of studies. Loose seton was not reported as a third treatment in any studies. IQR: Interquartile range.