Application of enhanced recovery after surgery in perioperative care of infants and children with Hirschsprung disease

Table 1 Inclusion and exclusion criteria

Inclusion criteria

Exclusion criteria

(1) Age less than 6 years old; (2) Diagnosis of HD according to the guidelines of the American Pediatric Surgical Association Hirschsprung Disease Interest Group[21], based on full-thickness biopsy findings of the absence of mucosal and submucosal ganglion cells away from the dentate line; (3) Pathological type includes only common type; (4) Barium enema showing significant dilation of the rectosigmoid colon and the existence of a stricture segment, and intraoperative findings showing obvious thickening of the dilated colon and dark red or purple in color; (5) Anorectal manometry stimulated by balloon inflation showing absence of the anorectal inhibitory reflex; (6) Characteristic clinical manifestations, including intractable constipation, abdominal distension, and delayed fecal discharge; and (7) Treatment with the Soave procedure via the laparoscope

(1) Systemic comorbidities, such as congenital heart disease, nephrotic syndrome, glomerulonephritis, pneumonia, and severe liver insufficiency; (2) Serious infection or blood or immune system diseases; (3) Severe hypoproteinemia, anemia, or inadequate remission after treatment; and (4) Refusal to participate in the ERAS study by the parents

HD: Hirschsprung disease; ERAS: Enhanced recovery after surgery.