Case Control Study
Copyright ©The Author(s) 2025.
World J Gastrointest Surg. Jun 27, 2025; 17(6): 104652
Published online Jun 27, 2025. doi: 10.4240/wjgs.v17.i6.104652
Table 3 Postoperative morbimortality among the three groups, n (%)

EDS group (n = 129)
IDS group (n = 71)
NDS group (n = 44)
P value
C-reactive protein, mg/dL, 3rd day14.6 (0.1-39)20.4 (2-57)10.3 (0.6-33.6)0.054
Medical complications39 (30.3)24 (33.8)17 (38.6)0.307
Surgical complications
Wound infection20 (15.5)12 (16.9)4 (9.3)0.515
Postoperative pancreatic fistula0.009
Grade A/non-POPF108 (83.7)50 (70.5)36 (81.8)
Grade B19 (14.7)11 (15.5)4 (9.1)
Grade C2 (1.6)10 (14.1)4 (9.1)
Delayed gastric emptying0.195
Grade A20 (15.5)12 (16.9)10 (22.7)
Grade B20 (15.5)19 (26.8)6 (13.6)
Grade C7 (5.4)4 (5.6)0 (0)
No delayed gastric emptying82 (63.6)36 (50.7)28 (63.6)
Postoperative hemorrhage0.460
Grade A6 (4.7)4 (5.6)2 (4.5)
Grade B7 (5.4)3 (4.2)4 (9.1)
Grade C3 (2.3)5 (7)4 (9.1)
No postoperative hemorrhage113 (87.6)59 (83.1)34 (77.3)
Reoperations16 (12.4)14 (19.7)9 (20.5)0.063
Hemoperitoneum3 (2.3)4 (5.6)4 (9.1)
Pancreatic fistula2 (1.6)10 (14.1)4 (9.1)
Jejunostomy3 (2.3)0 (0)0 (0)
Other8 (6.2)0 (0)1 (2.3)
Complications, Clavien-Dindo classification
Grade I-II74 (57.3)18 (40.9)25 (35.2)0.007
Grade III-IV26 (20.1)13 (29.5)23 (32.5)0.149
Intensive care unit stay, days2 (1-15)2 (1-30)2 (1-30)0.157
Hospital stay, days17 (5-78)20 (7-97)18 (5-59)0.089
Follow-up
Mortality, 90 days2 (1.6)4 (5.6)2 (4.5)0.046
Morbidity, 90 days90 (70.3)42 (59.1)30 (73.2)0.436
De novo endocrine insufficiency16 (12.4)15 (21.1)6 (13.6)0.293
De novo exocrine insufficiency53 (41.1)30 (42.3)19 (43.2)0.217
Venous thrombosis4 (3.1)5 (7)3 (6.8)0.142
Pulmonary embolism4 (3.1)2 (2.8)0 (0)0.204
Adjuvant chemotherapy62 (48)34 (47.9)22 (50)0.975