Case Control Study
Copyright ©The Author(s) 2025.
World J Gastrointest Surg. Jun 27, 2025; 17(6): 104652
Published online Jun 27, 2025. doi: 10.4240/wjgs.v17.i6.104652
Table 2 Perioperative variables and histological features among the three groups, n (%)
Variable/feature
EDS group (n = 129)
IDS group (n = 71)
NDS group (n = 44)
P value
Duration of surgery, minutes370 (190-590)430 (300-748)415 (240-710)0.001
Patient transfused14 (10.6)19 (26.8)6 (13.6)0.036
Surgical findings/techniques
Caliber of Wirsung duct, mm3.5 (1-13)3 (2-10)5 (1-17)0.001
Consistency of the pancreas< 0.001
Hard60 (46.5)20 (28.2)31 (70.5)
Soft38 (29.5)16 (22.5)5 (11.4)
Normal31 (24)35 (49.3)8 (18.1)
Pylorus preservation55 (42.6)41 (57.7)26 (59.1)0.051
Vascular resection12 (9.3)6 (8.5)5 (11.4)0.872
Type of reconstruction0.119
One intestinal loop99 (76.7)64 (90.1)37 (86)
Two intestinal loops30 (23.3)7 (9.9)6 (14)
Histological features
Type of tumor0.558
Adenocarcinoma89 (68.9)50 (70.4)29 (65.9)
Cholangiocarcinoma10 (7.7)4 (5.6)3 (6.8)
Neuroendocrine6 (4.6)4 (5.6)4 (9.1)
Other24 (18.6)13 (18.3)8 (18.2)
Degree of differentiation0.991
Good32 (24.8)17 (23.9)11 (25)
Moderate45 (34.9)30 (42.3)20 (45.5)
Poor19 (14.7)12 (16.9)7 (15.9)
Not valuable33 (25.6)12 (16.9)6 (13.6)
Tumor invasion0.339
In situ2 (1.5)1 (1.4)2 (4.5)
< 2 cm20 (15.5)14 (19.7)10 (22.7)
> 2 cm, limited to pancreas36 (27.9)28 (39.4)10 (22.7)
Peripancreatic invasion44 (34.1)20 (18.2)17 (38.6)
Invasion at CA or SMA6 (4.6)1 (1.4)0 (0)
Lymph node invasion71 (55)38 (53.5)25 (56.8)0.938
Number of resected nodes15 (11-38)15 (10-53)13 (8-78)0.602
Number of positive nodes1 (0-11)1 (0-14)1.5 (0-8)0.707
Macrovascular invasion18 (13.9)12 (16.9)8 (18.2)0.961
Microvascular invasion48 (37.2)27 (38)16 (36.4)0.961
Neural invasion61 (47.3)35 (49.3)16 (36.4)0.228
R0 resection84 (65.1)48 (67.6)24 (54.5)0.361
Tumor staging
IA7 (6.7)8 (13.1)4 (10.3)
IB8 (7.6)11 (18)0 (0)
IIA11 (10.5)5 (8.2)7 (17.9)
IIB41 (39)15 (24.6)17 (43.6)
III15 (14.3)11 (18)3 (7.7)
IV4 (3.8)2 (3.3)2 (5.1)