Relationship between prognosis and glucose transporter-1 and Ki-67 expression in obstructive colon cancer pre and post stent placement

Table 2 Univariate and multivariate analysis of cliniopathologic parameters on 3-year recurrence-free interval

Parameters	3-year recurrence-free interval
	Univariate analysis			Multivariate analysis
	HR	95%CI	P value	HR	95%CI	P value
Age (≥ 65 vs < 65)	1.544	0.679-3.553	0.297
Sex (female vs male)	0.476	0.189-1.200	0.115
Location (sigmoid vs transverse to descending)	0.589	0.234-1.487	0.263
Differentiation (well and moderately vs poorly)	0.046	0-208.005	0.474
Lymphovascular invasion (absence vs presence)	3.352	1.497-7.508	0.030a	0.570	0.130-2.495	0.455
Perineural invasion (absence vs presence)	2.600	1.164-5.809	0.020a	1.963	0.500-7.698	0.334
pT stage (T3 vs T4)	30.671	0.540-1742.052	0.097
pN stage (absence vs presence)	4.841	1.442-16.247	0.011a	3.876	1.018-14.684	0.047a
pTNM stage (Ⅱ vs Ⅲ)	4.841	1.442-16.247	0.011a
Ki67 (pre-SEMS) (high vs low)	0.496	0.222-1.106	0.087
Ki67 (post-SEMS) (high vs low)	0.752	0.329-1.720	0.500
GLUT1 (pre-SEMS) (high vs low)	2.710	1.067-6.885	0.036a	3.490	1.165-10.453	0.026a
GLUT1 (post-SEMS) (high vs low)	4.317	1.709-10.904	0.002a	4.335	1.539-12.214	0.006a
Duration of CAPOX (3 months vs 6 months)	1.442	0.640-3.250	0.377

^aP < 0.05.

Ki67: High (expression level ≥ 30%) vs low (expression level < 30%); GLUT-1: High (scores of 3) vs low (scores of 0-2). GLUT-1: Glucose transporter-1; SEMS: Self-expanding metallic stent.