Relationship between prognosis and glucose transporter-1 and Ki-67 expression in obstructive colon cancer pre and post stent placement

Table 1 Relationship between glucose transporter-1 expression and various patient characteristics (n = 71), n (%)

Clinicopathologic parameters	Total cases (%)	GLUT-1 (pre-SEMS)			GLUT-1 (post-SEMS)
		High (%)	Low (%)	P value	High (%)	Low (%)	P value
	71 (100)	10 (14.1)	61 (85.9)		31 (43.7)	40 (56.3)
Age
< 65	31 (43.7)	6 (60.0)	25 (41.0)	0.435	17 (54.8)	14 (35.0)	0.095
≥ 65	40 (56.3)	4 (40.0)	36 (59.0)		14 (45.2)	26 (65.0)
Sex
Female	28 (39.4)	3 (30.0)	25 (41.0)	0.757	11 (35.5)	17 (42.5)	0.549
Male	43 (60.6)	7 (70.0)	36 (59.0)		20 (64.5)	23 (57.5)
Location
Sigmoid	48 (67.6)	8 (80.0)	40 (65.6)	0.590	20 (64.5)	28 (70.0)	0.624
Transverse to descending	23 (32.4)	2 (20.0)	21 (34.4)		11 (35.5)	12 (30.0)
Differentiation
Well and moderately	68 (95.8)	10 (100.0)	58 (95.1)	0.630	31 (100.0)	37 (92.5)	0.335
Poorly	3 (4.2)	0 (0)	3 (4.9)		0 (0)	3 (7.5)
Lymphovascular invasion
Absence	51 (71.8)	5 (50.0)	46 (75.4)	0.202	17 (54.8)	34 (85.0)	0.003a
Presence	20 (28.2)	5 (50.0)	15 (24.6)		14 (45.2)	6 (15.0)
Perineural invasion
Absence	48 (67.6)	4 (40.0)	44 (72.1)	0.099	19 (61.3)	29 (72.5)	0.317
Presence	23 (32.4)	6 (60.0)	17 (27.9)		12 (38.7)	11 (27.5)
pT stage
T3	14 (19.7)	3 (30.0)	11 (18.0)	0.651	3 (9.7)	11 (27.5)	0.061
T4	57 (80.3)	7 (70.0)	50 (82.0)		28 (90.3)	29 (72.5)
pN stage
Absence	25 (35.2)	3 (30.0)	22 (36.1)	0.988	8 (25.8)	17 (42.5)	0.144
Presence	46 (64.8)	7 (760.0)	39 (63.9)		23 (74.2)	23 (57.5)
pTNM stage
Ⅱ	25 (35.2)	3 (30.0)	22 (36.1)	0.988	8 (25.8)	17 (42.5)	0.144
Ⅲ	46 (64.8)	7 (70.0)	39 (63.9)		23 (74.2)	23 (57.5)
Ki67 (pre-SEMS)
High	45 (63.4)	8 (80.0)	37 (60.7)	0.101	20 (64.5)	25 (62.5)	0.861
Low	26 (36.6)	2 (20.0)	24 (29.3)		11 (35.5)	15 (37.5)
Ki67 (post-SEMS)
High	47 (66.2)	8 (80.0)	39 (63.9)	0.562	21 (67.7)	26 (65.0)	0.809
Low	24 (33.8)	2 (20.0)	22 (36.1)		10 (32.3)	14 (35.0)
Interval time
< 3 weeks	60 (84.5)	7 (11.7)	53 (88.3)	0.370	27 (45.0)	33 (54.5)	0.841
≥ 3 weeks	11 (15.5)	3 (27.3)	8 (72.3)		4 (36.4)	7 (63.6)

^aP < 0.05.

Ki67: High (expression level ≥ 30%) vs low (expression level < 30%); GLUT-1: High (scores of 3) vs Low (scores of 0-2). GLUT-1: Glucose transporter-1; SEMS: Self-expandable metallic stent.