Predictive model and prognostic insights into duodenal stump fistula following radical gastrectomy with Roux-en-Y reconstruction for gastric cancer

Table 3 Univariate logistic regression analysis of the duodenal stump fistula risk factors

Variables (clinicopathological factors)	P value	Variables (perioperative factors)	P value
Age	< 0.001b	Non-anastomotic complications1	0.073
BMI	0.945	Anastomotic complications2	1
Gender	0.310	Surgical approach	0.190
ASA score	0.757	Laparoscopic surgery	0.084
OVF	< 0.001b	Conversion to open surgery	1
Heart failure or angina	1	Gastrectomy	0.622
History of bowel obstruction	1	Lymphadenectomy extent	1
History of digestive ulcer	1	Combined resection	1
History of abdominal surgery	0.777	Surgical time	0.350
CEA	0.494	Blood loss	0.020a
CA-199	0.033a	Retrieved lymph nodes	0.423
AFP	0.042a	Reinforcement of duodenal stump	1
Tumor location	0.735	Embedding degree	0.142
Tumor diameter	0.394	Muscularis and serosa injury	0.395
Pathology type	0.912	Bleeding in reinforcement	0.790
pT	0.276	Reinforcement duration of duodenal stump	1
pN	0.582	Stump suture-fixed to the intestinal wall	0.100
Distant metastasis	1
pStage	0.505

^aP < 0.05.

^bP < 0.001.

¹≥ Grade 3a.

²≥ Grade 3a and except duodenal stump fistula.

AFP: Alpha-fetoprotein; ASA: American Society of Anesthesiologists; BMI: Body mass index; CA-199: Carbohydrate antigen 199; CEA: Carcinoembryonic antigen; OVF: Obstructive ventilatory failure; pN: Pathological nodal stage; pT: Pathological tumor stage.