Effect of dexmedetomidine-ropivacaine transversus abdominis plane block on analgesia and cognitive impairment risk in colorectal cancer surgery

Table 3 Comparison of serum inflammatory factor levels between two groups

Time point	Group	IL-6 (pg/mL)	TNF-α (pg/mL)	CRP (mg/L)
1 day before surgery	Observation	12.45 ± 3.15	8.73 ± 2.22	3.45 ± 1.02
	Control	12.39 ± 3.09	8.69 ± 2.18	3.42 ± 0.98
6 hours after surgery	Observation	26.78 ± 5.32	16.45 ± 3.47	7.89 ± 2.15
	Control	35.12 ± 6.48	22.67 ± 4.56	10.34 ± 2.87
24 hours after surgery	Observation	18.65 ± 4.08	12.34 ± 2.98	5.23 ± 1.65
	Control	25.78 ± 5.21	17.89 ± 3.84	7.68 ± 2.12
48 hours after surgery	Observation	14.32 ± 3.67	10.12 ± 2.45	4.12 ± 1.34
	Control	19.65 ± 4.35	13.78 ± 3.12	5.89 ± 1.78
Time main effect F value		87.452	92.678	79.345
Time main effect P value		< 0.001	< 0.001	< 0.001
Group main effect F value		36.541	41.763	34.217
Group main effect P value		< 0.001	< 0.001	< 0.001
Interaction F value		9.328	10.456	8.974
Interaction P value		< 0.001	< 0.001	< 0.001

P < 0.05 indicated significant difference. IL-6: Interleukin-6; TNF-α: Tumor necrosis factor-α; CRP: C-reactive protein.