Novel inflammatory-nutritional prognostic index for advanced gastric cancer patients undergoing gastrectomy and prophylactic hyperthermic intraperitoneal chemotherapy

Figure 2 Construction of the inflammatory-nutritional prognostic index using the least absolute shrinkage and selection operator Cox regression model. A: The least absolute shrinkage and selection operator coefficient curves of 12 inflammatory and nutritional indicators, showing the changes in the regression coefficients of each indicator in the model. As the regularization parameter λ increases, some coefficients are gradually shrunk to zero, thus achieving variable selection and enhancing the sparsity of the model; B: Ten-fold cross-validation was used for parameter tuning and selection of the least absolute shrinkage and selection operator model. The vertical "dotted line a" represents λmin, that is, the number of independent variables in the model corresponding to the minimum error. It indicates that under the λ =0.041, the cross-validation error of the model reaches the minimum. The vertical "dotted line b" represents λ1se, which is the number of independent variables in the model corresponding to the position of one standard error from the minimum error.